A novel calreticulin of Psoroptes ovis regulated keratinocyte function resulting in host skin barrier dysfunction: implications for involvement in the pathogenesis of psoroptic mange
PsoCRT disrupted the physical and immune barriers of keratinocytes, leading to skin dysfunction and facilitating a microenvironment conducive to P. ovis parasitization, thereby highlighting its important role in the pathogenesis of psoroptic mange.
Authors
- Guiying Hao (ORCID: https://orcid.org/0000-0003-0233-4947)
- Fangyan Wu
- Yue Xie (ORCID: https://orcid.org/0000-0001-9062-6928)
- Jing Xu (ORCID: https://orcid.org/0000-0002-6990-8602)
- Xiaobin Gu (ORCID: https://orcid.org/0000-0003-4540-2102)
- Ran He (ORCID: https://orcid.org/0000-0003-0203-0337)
- Yane Li
- Xiangyue Yao
- Youping Liang
- Je Fan
- Hui Wang (ORCID: https://orcid.org/0000-0001-8478-9990)
Institutions
- Sichuan Agricultural University (CN)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1186/s13071-025-06800-4
- Primary Topic
- Dermatological diseases and infestations
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sichuan Agricultural University