Type 2 diabetes polygenic risk score interactions with lifestyle risk factors in Black Americans
These results contribute to understanding the relationship between genetics and other T2D risk factors in Black Americans who have a high burden of T2D, potentially informing targeted prevention strategies.
Authors
- Mariah Meyer (ORCID: https://orcid.org/0000-0001-9635-5196)
- Maggie A. Stanislawski (ORCID: https://orcid.org/0000-0001-7768-8868)
- Sridharan Raghavan (ORCID: https://orcid.org/0000-0003-0643-4873)
- Steven Buyske (ORCID: https://orcid.org/0000-0001-8539-5416)
- E.M. Lange
- Boya Guo (ORCID: https://orcid.org/0000-0002-8508-4084)
- Vinodh Srinivasasainagendra
- Kristin L. Young (ORCID: https://orcid.org/0000-0003-0070-6145)
- Elizabeth Litkowski (ORCID: https://orcid.org/0000-0002-7079-696X)
- Hemant K. Tiwari
- Loı̈c Le Marchand (ORCID: https://orcid.org/0000-0001-5013-980X)
- Ulrike Peters (ORCID: https://orcid.org/0000-0001-5666-9318)
- Stephanie Waldrop (ORCID: https://orcid.org/0000-0001-7654-2816)
- Nicole D. Armstrong (ORCID: https://orcid.org/0000-0002-6483-4560)
- Marguerite R. Irvin (ORCID: https://orcid.org/0000-0002-1442-2023)
- Burcu F. Darst (ORCID: https://orcid.org/0000-0002-6205-4632)
- Stephen S. Rich
- Iona C. Cheng (ORCID: https://orcid.org/0000-0003-4132-2893)
- Yanwei Cai (ORCID: https://orcid.org/0000-0002-3950-3794)
- Heather M. Highland (ORCID: https://orcid.org/0000-0002-3583-8239)
- Ashley W. Scadden (ORCID: https://orcid.org/0000-0001-7603-1442)
- Mariaelisa Graff
- Myriam Fornage (ORCID: https://orcid.org/0000-0003-0677-8158)
- Christopher A. Haiman
- Charles Kooperberg
- Jerome I. Rotter
- K.E. North (ORCID: https://orcid.org/0000-0002-8903-0366)
- Aastha Kakar (ORCID: https://orcid.org/0009-0001-5192-1286)
- Leslie A. Lange
Institutions
- Rutgers, The State University of New Jersey (US)
- University of North Carolina at Chapel Hill (US)
- University of Southern California (US)
- University of California, San Francisco (US)
- University of Michigan (US)
- UCLA Medical Center (US)
- University of Alabama at Birmingham (US)
- Fred Hutch Cancer Center (US)
- Cancer Center of Hawaii (US)
- Brown Foundation (US)
- University of Virginia (US)
- University of Colorado Anschutz Medical Campus (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Lifestyle Genomics
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1159/000546100
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Health and Human Services
- Jackson State University
- Mississippi State Department of Health
- National Institutes of Health
- National Heart, Lung, and Blood Institute
- National Human Genome Research Institute
- National Cancer Institute
- National Institute on Minority Health and Health Disparities