Dietary Protein Intake Recommendations for Patients with Non–Dialysis-Dependent CKD

Protein intake is crucial to maintain human health, and an adequate quantity and quality of dietary protein intake (DPI) is particularly important in patients with CKD. Both an insufficient amount of DPI ( i.e ., <0.6 g/kg body weight (body wt)/d) and an excess amount of DPI ( i.e ., >1.3 g/kg body wt/d) pose potential health hazards in patients with CKD stages 3-5. Therefore, to optimize patient outcomes, healthcare providers should be familiar with the effects of both inadequate and excessive DPI in this population. The Kidney Disease Outcome Quality Initiative guidelines on DPI are rooted in detailed analyses of available scientific evidence and provide detailed recommendations regarding different dietary interventions strategies to achieve optimal quantity and quality of DPI. The more recent Kidney Disease Improving Global Outcomes guidelines on CKD management have a substantially broader scope and include a relatively brief section on diet, recommending a DPI of 0.8 g/kg body wt/d, emphasizing the need to avoid a DPI of >1.3 g/kg body wt/d. Besides aiming for a DPI of approximately 0.6-0.8 g/kg body wt/d in patients with CKD stages 3-5, successful practical implementation of dietary interventions requires an individualized approach which considers patient characteristics, such as sociocultural norms, habitual dietary habits, and nutrition literacy as well as systemic factors such as feasibility and availability of interventions.

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Publication Details

Journal
Clinical Journal of the American Society of Nephrology
Published
2025-05-30
DOI
https://doi.org/10.2215/cjn.0000000772
Citations
1
Primary Topic
Dialysis and Renal Disease Management
Type
article
Field-Weighted Citation Impact
1.43
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article

Dietary Protein Intake Recommendations for Patients with Non–Dialysis-Dependent CKD

Denis Fouque, Linda W. Moore, Giacomo Garibotto, Brandon M. Kistler et al.
1 citations
Clinical Journal of the American Society of Nephrology
Dialysis and Renal Disease Management
1.43
article

Dietary Protein Intake Recommendations for Patients with Non–Dialysis-Dependent CKD

Denis Fouque, Linda W. Moore, Giacomo Garibotto, Brandon M. Kistler, Kelly Lambert, S. Russ Price, T. Alp İkizler, Kamyar Kalantar‐Zadeh, Angela Yee‐Moon Wang, Joel D. Kopple, Csaba Pal Kovesdy, Giuliano Brunori, Laetitia Koppe, Allon N. Friedman, Robert H. Mak, Martin K. Kuhlmann
article en
1 citations

Abstract

Protein intake is crucial to maintain human health, and an adequate quantity and quality of dietary protein intake (DPI) is particularly important in patients with CKD. Both an insufficient amount of DPI ( i.e ., <0.6 g/kg body weight (body wt)/d) and an excess amount of DPI ( i.e ., >1.3 g/kg body wt/d) pose potential health hazards in patients with CKD stages 3-5. Therefore, to optimize patient outcomes, healthcare providers should be familiar with the effects of both inadequate and excessive DPI in this population. The Kidney Disease Outcome Quality Initiative guidelines on DPI are rooted in detailed analyses of available scientific evidence and provide detailed recommendations regarding different dietary interventions strategies to achieve optimal quantity and quality of DPI. The more recent Kidney Disease Improving Global Outcomes guidelines on CKD management have a substantially broader scope and include a relatively brief section on diet, recommending a DPI of 0.8 g/kg body wt/d, emphasizing the need to avoid a DPI of >1.3 g/kg body wt/d. Besides aiming for a DPI of approximately 0.6-0.8 g/kg body wt/d in patients with CKD stages 3-5, successful practical implementation of dietary interventions requires an individualized approach which considers patient characteristics, such as sociocultural norms, habitual dietary habits, and nutrition literacy as well as systemic factors such as feasibility and availability of interventions.

Clinical Journal of the American Society of NephrologyVol. 20(8)
Université Claude Bernard Lyon 1 (FR), Inserm (FR), University of Tennessee Health Science Center (US), National University of Singapore (SG), East Carolina University (US), University of Trento (IT), University of Wollongong (AU), Cornell University (US), Purdue University West Lafayette (US), Singapore General Hospital (SG), UCLA Health (US), UCLA Medical Center (US), University of California San Diego (US), Memphis VA Medical Center (US), Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR), Hospices Civils de Lyon (FR), Methodist Hospital (US), Provincia Autonoma di Trento (IT), Centre de Recherche en Nutrition Humaine Rhône-Alpes (FR), Laboratoire de recherche en cardiovasculaire, métabolisme, diabétologie et nutrition (FR), Klinikum im Friedrichshain (DE), Harbor–UCLA Medical Center (US), Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US), University of Genoa (IT), Vanderbilt University Medical Center (US)
Quality Education
Openalex Percentile: Top 19%
Dialysis and Renal Disease Management
1.43
DOISourceOpenAlex
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