Is L-dopa test effective in detecting adrenal insufficiency with preliminary diagnosis of growth hormone deficiency in children with short stature?
The L-dopa stimulation test may represent a valuable adjunctive tool for the evaluation of cortisol sufficiency in children undergoing assessment for suspected GH deficiency. However, further prospective studies with larger sample sizes and standardized protocols are warranted to validate its diagnostic accuracy and clinical utility in detecting adrenal insufficiency.
Authors
- Gülümay Vural Topaktaş (ORCID: https://orcid.org/0000-0001-8996-1251)
- Bumin Nuri Dündar (ORCID: https://orcid.org/0000-0002-7506-061X)
- Eren Er (ORCID: https://orcid.org/0000-0003-4770-0365)
- Sevim Onguner (ORCID: https://orcid.org/0000-0001-6841-6203)
- Benay Turan (ORCID: https://orcid.org/0000-0002-6947-6782)
Institutions
- Izmir University (TR)
- Izmir Kâtip Çelebi University (TR)
Publication Details
- Journal
- Journal of Pediatric Endocrinology and Metabolism
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1515/jpem-2025-0143
- Primary Topic
- Growth Hormone and Insulin-like Growth Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00