Effects of extreme heat exposure on heatstroke and liver injury in mice: The role of PPARα
PPARα played an essential role in extreme heat exposure-induced heatstroke and liver injury, and PPARα intervention conferred protection against it via inhibition of ferroptosis. https://doi.org/10.1289/EHP15326.
Authors
- Kunyi Wang
- Cuiqing Liu (ORCID: https://orcid.org/0000-0002-0393-7806)
- Tong Hou
- Ran Li (ORCID: https://orcid.org/0000-0002-6268-8811)
- Qinghua Sun (ORCID: https://orcid.org/0000-0001-5029-587X)
- Kezhong Zhang (ORCID: https://orcid.org/0000-0002-4437-1095)
- Renjie Hu (ORCID: https://orcid.org/0000-0003-3444-071X)
- Lu Zhang (ORCID: https://orcid.org/0000-0002-1137-8055)
- Guoqing Zhang (ORCID: https://orcid.org/0000-0003-0821-8787)
- Jiahui Wang (ORCID: https://orcid.org/0000-0002-0867-8612)
- Lisha Zhao (ORCID: https://orcid.org/0000-0002-6115-7074)
- Xiuyu Ji
Institutions
- Zhejiang Chinese Medical University (CN)
- Wayne State University (US)
- Sichuan University (CN)
- China International Science and Technology Cooperation (CN)
- West China Hospital of Sichuan University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Environmental Health Perspectives
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1289/ehp15326
- Citations
- 4
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 4.66
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Sichuan Province