The Impact of the Selective Cytopheretic Device on Neutrophil-to-Lymphocyte Ratios and Hematological Parameters in Acute Kidney Injury: A Pooled Analysis
In a pooled analysis of multiple AKI adult clinical studies, SCD treatment demonstrated reductions in NLR. This analysis provides further clinical mechanistic evidence of leukocyte immunomodulation in targeting the dysregulation of effector immune cells in hyperinflammatory conditions such as AKI and sepsis. .
Authors
- Jay L. Koyner (ORCID: https://orcid.org/0000-0001-6873-8712)
- H. David Humes
- Seethalakshmi Iyer
- Nicholas J. Ollberding (ORCID: https://orcid.org/0000-0001-9404-7368)
- Lenar Yessayan (ORCID: https://orcid.org/0000-0002-8955-1292)
- Kevin K. Chung (ORCID: https://orcid.org/0000-0002-2781-3787)
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- University of Michigan (US)
- University of Chicago (US)
- Michigan Medicine (US)
- SEAKR Engineering (United States) (US)
Publication Details
- Journal
- The Nephron journals/Nephron journals
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1159/000546528
- Citations
- 1
- Primary Topic
- COVID-19 Impact on Reproduction
- Type
- article
- Field-Weighted Citation Impact
- 2.06
Funders
- American Society of Nephrology