Identification and Validation of Key Genes Involved in the Coupling of Mitochondria-Associated Endoplasmic Reticulum Membrane in Hemorrhoidal Disease

This study identifies <i>MUC16</i> and <i>DEFA5</i> as key genes associated with HD and MAM and presents a predictive nomogram with high accuracy. These findings provide novel insights into the mechanisms and potential treatment targets for HD.

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Publication Details

Journal
International Journal of General Medicine
Published
2025-05-01
DOI
https://doi.org/10.2147/ijgm.s511281
Citations
1
Primary Topic
Anorectal Disease Treatments and Outcomes
Type
article
Field-Weighted Citation Impact
2.01
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article

Identification and Validation of Key Genes Involved in the Coupling of Mitochondria-Associated Endoplasmic Reticulum Membrane in Hemorrhoidal Disease

Zhijing Rao, Lanyu Chen, Jun Yang, Li Mao et al.
1 citations
International Journal of General Medicine
Anorectal Disease Treatments and Outcomes
2.01
article

Identification and Validation of Key Genes Involved in the Coupling of Mitochondria-Associated Endoplasmic Reticulum Membrane in Hemorrhoidal Disease

Zhijing Rao, Lanyu Chen, Jun Yang, Li Mao, Junmei He, Zhi Zheng, Yanru Wang
article en
1 citations

Abstract

This study identifies <i>MUC16</i> and <i>DEFA5</i> as key genes associated with HD and MAM and presents a predictive nomogram with high accuracy. These findings provide novel insights into the mechanisms and potential treatment targets for HD.

International Journal of General MedicineVol. Volume 18
First Affiliated Hospital of Jiangxi Medical College (CN), Jiangxi Provincial People's Hospital (CN)
Zero hunger
Openalex Percentile: Top 15%
Anorectal Disease Treatments and Outcomes
2.01
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