Diverse modes of ceftazidime/avibactam resistance acquisition in carbapenem-resistant Klebsiella pneumoniae and Pseudomonas aeruginosa from a Chinese intensive care unit
In CRKP and CRPA, diverse resistance mechanisms contributed to CZA resistance. These CZA-resistant strains were transmitted among patients in the ICU and even across regions to the other healthcare unit when the patient was transferred.
Authors
- Xinhong Han (ORCID: https://orcid.org/0009-0004-4125-9075)
- Yunsong Yu (ORCID: https://orcid.org/0000-0003-2903-918X)
- Minhua Chen (ORCID: https://orcid.org/0000-0003-0513-1301)
- Junxin Zhou
- Xiaoxing Du (ORCID: https://orcid.org/0000-0003-3608-195X)
- Xiaoting Hua (ORCID: https://orcid.org/0000-0001-8215-916X)
- Rui Weng (ORCID: https://orcid.org/0000-0002-2519-2745)
- Min Liang (ORCID: https://orcid.org/0000-0003-3603-861X)
- Yue Li (ORCID: https://orcid.org/0000-0001-6161-1196)
- Weiping Wang (ORCID: https://orcid.org/0000-0003-0853-1749)
- Yan Jiang (ORCID: https://orcid.org/0000-0002-5877-9286)
- Zhihui Zhou (ORCID: https://orcid.org/0000-0002-9582-3688)
Institutions
- Nanjing General Hospital of Nanjing Military Command (CN)
- Sir Run Run Shaw Hospital (CN)
- Zhejiang Cancer Hospital (CN)
- Zhejiang University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Annals of Clinical Microbiology and Antimicrobials
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1186/s12941-025-00800-z
- Citations
- 7
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 4.14
Funders
- National Natural Science Foundation of China
- Zhejiang University
- Natural Science Foundation of Zhejiang Province