A Retrospective Study of Ultramassive Transfusion in Trauma Patients: Is There a Value After Which Additional Transfusions Are Futile?
In this study, patients who received UMT had higher mortality and worse outcomes than those who received fewer units. However, this study did not identify a threshold beyond which all patients died and therefore cannot justify implementing a limit on the number of RBC units transfused based on these data alone.
Authors
- John T. Simpson (ORCID: https://orcid.org/0000-0002-1081-5049)
- Danielle Tatum (ORCID: https://orcid.org/0000-0002-3281-3853)
- Claudia Álvarez (ORCID: https://orcid.org/0000-0002-6713-3823)
- Damon Clark (ORCID: https://orcid.org/0000-0003-4274-0296)
- Mandeep Singh (ORCID: https://orcid.org/0000-0003-4474-4581)
- Trevor A. Pickering (ORCID: https://orcid.org/0000-0002-2281-641X)
- Rania Elkhateb (ORCID: https://orcid.org/0000-0003-0559-4525)
- Siddharth Singh (ORCID: https://orcid.org/0000-0003-3826-6616)
- Yassin Bahgat
- Olga Kaslow
- Erika Tay-Lasso
- Joy L. Chen
- Kristen Stefanescu (ORCID: https://orcid.org/0000-0002-8773-9742)
- Catherine M. Kuza (ORCID: https://orcid.org/0000-0001-9403-7936)
- Richard L. Applegate (ORCID: https://orcid.org/0000-0002-1454-4549)
- Jeffry T. Nahmias (ORCID: https://orcid.org/0000-0003-0094-571X)
- Norma J. Klein
- Elizabeth A. H. Hall (ORCID: https://orcid.org/0000-0001-9572-9854)
- Jeffrey L. Tong
- Kenji Inaba
- Jianzhou Xiao
- Francis J. Major
- Farzin Ahmed
Institutions
- Tulane University (US)
- University of Southern California (US)
- University of California, Irvine (US)
- Medical College of Wisconsin (US)
- Loma Linda University (US)
- University of Chicago (US)
- Riverside Community Hospital (US)
- Harbor–UCLA Medical Center (US)
- University of Arkansas for Medical Sciences (US)
- University of California, Davis (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Anesthesia & Analgesia
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1213/ane.0000000000007569
- Citations
- 5
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 7.73