Interlaboratory study to assess precision and reproducibility of the meningococcal antigen surface expression (MEASURE) assay to quantify factor H binding protein expression at the surface of meningococcal serogroup B strains
Quantification of fHbp surface expression using the MEASURE assay is robust and reproducible across different laboratories. Previously determined cutoffs corresponding to predicted susceptibility to vaccine-induced antibodies can be applied to MEASURE data generated across laboratories.
Authors
- Paul Liberator (ORCID: https://orcid.org/0000-0001-8298-5779)
- S. A. Clark (ORCID: https://orcid.org/0000-0002-4916-3623)
- Kimberly Moss
- Charles Y. Tan (ORCID: https://orcid.org/0000-0001-8719-4669)
- Yamini Gorantla
- Panagiotis Maniatis (ORCID: https://orcid.org/0000-0001-5240-0848)
- Jakob Loschko
- Ray Borrow (ORCID: https://orcid.org/0000-0002-0691-6568)
- Jamie Findlow (ORCID: https://orcid.org/0000-0001-5153-4043)
- Karen Caroline Acerbi Garcia
- Jason Yip (ORCID: https://orcid.org/0000-0001-9980-0670)
- MaryAnn Murillo
Institutions
- Centers for Disease Control and Prevention (US)
- Pfizer (United States) (US)
- Pfizer (United Kingdom) (GB)
- Manchester Royal Infirmary (GB)
- Eagle Mount (US)
- CDC Foundation (US)
Publication Details
- Journal
- Diagnostic Microbiology and Infectious Disease
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1016/j.diagmicrobio.2025.116920
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 0.00