Clinical value of circulating bioactive adrenomedullin for prediction of outcome and hydrocortisone response in sepsis patients—a post-hoc analysis of the HYPRESS trial
Whereas bio-ADM levels are associated with sepsis outcomes, our data do not indicate usefulness of the marker to identify patients potentially benefitting from hydrocortisone therapy.
Authors
- Heba M. Elwi (ORCID: https://orcid.org/0000-0003-3763-2936)
- Patrick Meybohm (ORCID: https://orcid.org/0000-0002-2666-8696)
- Ludwig Christian Hinske (ORCID: https://orcid.org/0000-0001-7273-5899)
- Holger Bogatsch
- Stanislas Grassin‐Delyle (ORCID: https://orcid.org/0000-0001-5747-4432)
- Catherine M. Neumann (ORCID: https://orcid.org/0000-0002-9242-6505)
- Henri-Jean Garchon
- Camille Roquencourt (ORCID: https://orcid.org/0000-0002-0218-6086)
- Jihene Mahmoud
- Frank Bloos (ORCID: https://orcid.org/0000-0002-0767-7941)
- Markus Loeffler (ORCID: https://orcid.org/0000-0002-0424-9933)
- Josef Briegel (ORCID: https://orcid.org/0000-0003-2837-8008)
- Sandra Frank (ORCID: https://orcid.org/0000-0002-1749-0339)
- Karine Zeitouni (ORCID: https://orcid.org/0000-0002-5602-6942)
- Thorsten Brenner (ORCID: https://orcid.org/0000-0002-4570-877X)
- Robert B. Hash
- Christian Putensen (ORCID: https://orcid.org/0000-0003-1599-9809)
- Jérôme Fleuriet (ORCID: https://orcid.org/0000-0003-2076-1600)
- Dorothea Lange
- Carlos Flores (ORCID: https://orcid.org/0000-0001-5352-069X)
- Rahma Hellali (ORCID: https://orcid.org/0000-0002-1306-4682)
- Nicolas Hunzinger
- Michael Vogeser (ORCID: https://orcid.org/0000-0002-2745-2475)
- Margit Leitner
- Matthias Gründling
- Michael W Bauer (ORCID: https://orcid.org/0000-0002-1521-3514)
- Djillali Annane (ORCID: https://orcid.org/0000-0001-6805-8944)
- Gunnar Elke (ORCID: https://orcid.org/0000-0002-4948-1605)
- Manuela Adling-Ehrhardt (ORCID: https://orcid.org/0009-0002-3738-5250)
- Karidia Diallo (ORCID: https://orcid.org/0000-0001-7767-9638)
- Yasser Sadek Nassar (ORCID: https://orcid.org/0000-0002-5856-9131)
- Michael Kiehntopf
- Stefan Kluge (ORCID: https://orcid.org/0000-0001-8391-3988)
- Achim J. Kaasch (ORCID: https://orcid.org/0000-0002-6659-6738)
- Katharina Habler (ORCID: https://orcid.org/0000-0002-5110-346X)
- Marcus Oswald (ORCID: https://orcid.org/0000-0002-0740-7343)
- Virginie Maxime
- Shereen Elgengeehy
- Melanie Meersch (ORCID: https://orcid.org/0000-0002-6011-8049)
- Melissa E. Bauer
- Rania Bouneb
- Mohamed R. E. Aly (ORCID: https://orcid.org/0000-0002-0113-9392)
- Mohamed Gamal Elansary
- Elodie Lamy
- Pierre Moine
- Markus A. Weigand
- Jesús Villar
- Benedikt Frank (ORCID: https://orcid.org/0000-0001-8837-9489)
- Nicholas Heming
- Rainer König
- Christina Scharf-Janßen
- Sara Aly Abdelghany
- Zaineb Chelly-Dagdia
- Marie Alice Vovy
Institutions
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR)
- Université Paris-Saclay (FR)
- LMU Klinikum (DE)
- Assistance Publique – Hôpitaux de Paris (FR)
- CEA Paris-Saclay (FR)
- Hôpital Raymond-Poincaré (FR)
- Jena University Hospital (DE)
- Ludwig-Maximilians-Universität München (DE)
- Leipzig University (DE)
Publication Details
- Journal
- Infection
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1007/s15010-025-02569-x
- Primary Topic
- Adrenal Hormones and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bundesministerium für Bildung und Forschung
- Bundesministerium für Gesundheit
- Universitätsklinikum Jena
- Sphingotec GmbH
- South East Physics Network