Anesthesia isn’t sleep: The neuronal dynamics of immobility in isoflurane-anesthetized C. elegans differ from the activity patterns of previously established sleep-like quiescent states
Immobility is a fundamental characteristic of both anesthesia and naturally occurring sleep-states. However, we show that, in C. elegans, immobility in the anesthetized state is not produced by activating the innate neurological mechanism of quiescence.
Authors
- Andrew S. Chang
- Christopher V. Gabel (ORCID: https://orcid.org/0000-0002-2763-3938)
- Christopher W. Connor (ORCID: https://orcid.org/0000-0003-1735-641X)
- Laura Mazuera
Institutions
- Boston University (US)
- Brigham and Women's Hospital (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1371/journal.pone.0324323
- Citations
- 1
- Primary Topic
- Genetics, Aging, and Longevity in Model Organisms
- Type
- article
- Field-Weighted Citation Impact
- 0.95
Funders
- National Institute of General Medical Sciences