Colloidosome Based on Nanohydroxyapatite

A protocol for the preparation of fatty acid-functionalized nanohydroxyapatite was developed. These nanoparticles were characterized and used as building blocks for the preparation of Pickering water-in-oil emulsions, which in turn were used as a template for colloidosomes. It is possible to encapsulate proteins in these structures, and their low cellular toxicity was also demonstrated. These structures show structural fragility to pH and temperature changes.

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Publication Details

Journal
ACS Omega
Published
2025-05-30
DOI
https://doi.org/10.1021/acsomega.4c09144
Primary Topic
Pickering emulsions and particle stabilization
Type
article
Field-Weighted Citation Impact
0.00

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article

Colloidosome Based on Nanohydroxyapatite

Alfonso Garcı́a-Piñeres, Avinash J. Patil, Francisco A. Venegas, Mavis L. Montero et al.
ACS Omega
Pickering emulsions and particle stabilization
article

Colloidosome Based on Nanohydroxyapatite

Alfonso Garcı́a-Piñeres, Avinash J. Patil, Francisco A. Venegas, Mavis L. Montero, Mariana Elizondo-Vargas, Yéssica Elizondo
article en

Abstract

A protocol for the preparation of fatty acid-functionalized nanohydroxyapatite was developed. These nanoparticles were characterized and used as building blocks for the preparation of Pickering water-in-oil emulsions, which in turn were used as a template for colloidosomes. It is possible to encapsulate proteins in these structures, and their low cellular toxicity was also demonstrated. These structures show structural fragility to pH and temperature changes.

ACS OmegaVol. 10(22)
Universidad de Costa Rica (CR), University of Bristol (GB), Sociedade Brasileira de Química (BR)
Ministerio de Ciencia Tecnología y Telecomunicaciones, Consejo Nacional para Investigaciones Científicas y Tecnológicas, Vicerrectoría de Investigación, Universidad de Costa Rica
Openalex Percentile: Top 92%
Pickering emulsions and particle stabilization
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