Efficacy and side effect profiles of single versus divided doses of isotretinoin in acne vulgaris
Divided dosing of isotretinoin preserves efficacy while reducing conjunctivitis and erythema. If a single dose is preferred, evening administration may minimize ocular adverse events. These results support using divided or evening dosing to improve tolerability without compromising treatment outcomes. .
Authors
- Burak Çelik (ORCID: https://orcid.org/0000-0002-6746-4083)
- Düriye Deniz Demirseren (ORCID: https://orcid.org/0000-0002-4480-7792)
- Merve Kaya (ORCID: https://orcid.org/0000-0002-5188-1245)
Institutions
- Bilkent University (TR)
- John H. Stroger, Jr. Hospital of Cook County (US)
- City Hospital (GB)
Publication Details
- Journal
- Cutaneous and Ocular Toxicology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1080/15569527.2025.2511722
- Primary Topic
- Acne and Rosacea Treatments and Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00