Placental lesions in small for gestational age fetuses with and without clinical features of fetal growth restriction: a secondary analysis of the Doppler Ratio In fetal Growth restriction Intervention Trial At (near) Term (DRIGITAT) study
Among the small for gestational age infants, clinical features of fetal growth restriction are associated with high-grade maternal vascular malperfusion and high-grade fetal vascular malperfusion and the combined presence of these lesions. Both lesions may manifest antenatally with Doppler abnormalities (umbilicocerebral ratio>0.8 or umbilical artery pulsatility index>p90).
Authors
- Wessel Ganzevoort (ORCID: https://orcid.org/0000-0002-7243-2115)
- Mirthe H. Schoots (ORCID: https://orcid.org/0000-0003-2168-2517)
- Alexa A. Freedman (ORCID: https://orcid.org/0000-0001-9745-7768)
- Linda M. Ernst (ORCID: https://orcid.org/0000-0003-0104-5107)
- Sanne J. Gordijn (ORCID: https://orcid.org/0000-0003-3915-8609)
- Lotte E. van der Meeren (ORCID: https://orcid.org/0000-0002-4537-5645)
- Mauritia C Marijnen (ORCID: https://orcid.org/0000-0002-3500-578X)
- E Bazyleva
Institutions
- Northwestern University (US)
- University Medical Center Groningen (NL)
- NorthShore University HealthSystem (US)
- University of Groningen (NL)
- Leiden University Medical Center (NL)
- Ghent University Hospital (BE)
- Ghent University (BE)
- Amsterdam University Medical Centers (NL)
Publication Details
- Journal
- American Journal of Obstetrics and Gynecology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1016/j.ajog.2025.05.022
- Citations
- 3
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 6.17
Funders
- NorthShore University HealthSystem
- Amsterdam University Medical Centers
- Universiteit Leiden
- ZonMw
- Universiteit Gent
- Maastricht Universitair Medisch Centrum
- Leids Universitair Medisch Centrum
- Pritzker School of Medicine
- Faculty of Medicine and Health, University of Sydney