New insights into the adverse prognostic role of squamous differentiation in intrahepatic cholangiocarcinoma: A comprehensive analysis
These results suggest that squamous differentiation serves as an unfavorable prognosis factor in iCCA, and a threshold of 30 % for the squamous differentiation component can be considered to classify a tumor as adenosquamous carcinoma in iCCA.
Authors
- Kenichi Harada (ORCID: https://orcid.org/0000-0002-6451-0638)
- Dong Le Thanh
- Kaori Yoshimura
- Hiep Nguyen Canh (ORCID: https://orcid.org/0000-0002-0336-3339)
- Kenta Takahashi (ORCID: https://orcid.org/0000-0002-0910-4514)
- Shintaro Yagi (ORCID: https://orcid.org/0000-0001-7465-5761)
- Rui Yang (ORCID: https://orcid.org/0000-0002-3681-1839)
- Khuyen Nguyen Thi
- Quynh Nguyen Thi
- Zihan Li (ORCID: https://orcid.org/0009-0005-3543-3409)
- Tram Nguyen Thi
Institutions
- Kanazawa University (JP)
- Hanoi Medical University (VN)
Publication Details
- Journal
- Human Pathology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1016/j.humpath.2025.105824
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Education, Culture, Sports, Science and Technology
- Ministry of Health, Labour and Welfare
- Quỹ Đổi mới sáng tạo Vingroup
- Japan Society for the Promotion of Science