RNA binding proteins PCBP1 and PCBP2 regulate pancreatic β cell translation
Our findings demonstrate a requirement for the PCBPs in sustaining the global rates of mRNA translation critical for β cell control of glucose homeostasis.
Authors
- Doris A. Stoffers (ORCID: https://orcid.org/0000-0003-2626-2124)
- Matthew J. Varney (ORCID: https://orcid.org/0009-0006-4512-7306)
- Louis R. Ghanem (ORCID: https://orcid.org/0000-0002-7723-5241)
- Matthew W. Haemmerle
- Caroline C. Philpott (ORCID: https://orcid.org/0000-0002-1893-4739)
- Austin L. Good (ORCID: https://orcid.org/0000-0003-4922-6353)
- Kirill Batmanov
- Andrea V. Scota
- Sarah A. Tersey (ORCID: https://orcid.org/0000-0003-0667-2361)
- Sabyasachi Sen (ORCID: https://orcid.org/0000-0002-1685-4233)
- Alexander T Utecht
Institutions
- Children's Hospital of Philadelphia (US)
- University of Nis (RS)
- University of Chicago (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Molecular Metabolism
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1016/j.molmet.2025.102175
- Citations
- 3
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 6.02
Funders
- National Institute of Diabetes and Digestive and Kidney Diseases