CircSLC22A3 inhibits the invasion and metastasis of ESCC via the miR-19b-3p/TRAK2 axis and by reducing the stability of m6A-modified ACSBG1 mRNA
The present study identified circSLC22A3 as a new tumor suppressor that inhibited ESCC progression through both the circSLC22A3/ miR-19b-3p/ TRAK2 and circSLC22A3/ IGF2BP1/ ACSBG1 axes.
Authors
- Yan Qiao (ORCID: https://orcid.org/0000-0001-6357-8203)
- Kang Liu (ORCID: https://orcid.org/0000-0002-4640-0849)
- Jun Bie (ORCID: https://orcid.org/0000-0002-8296-0544)
- Ruolan Zhang (ORCID: https://orcid.org/0000-0003-4977-9468)
- Guiqin Song (ORCID: https://orcid.org/0000-0002-8068-4742)
- Yun Liu (ORCID: https://orcid.org/0000-0001-6026-169X)
- Jiayi Zhang (ORCID: https://orcid.org/0000-0002-0601-5794)
- Hang Yang (ORCID: https://orcid.org/0000-0001-8316-6572)
- Yingjie Pan (ORCID: https://orcid.org/0009-0009-4370-6648)
- Qiaoling Chen (ORCID: https://orcid.org/0000-0002-8120-195X)
Institutions
- North Sichuan Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1186/s12885-025-14390-8
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China