Evaluation of Pemafibrate Treatment in Improving Liver Function and Lipid Profiles in Patients with Steatotic Liver Disease: Case Series Study

Background: The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) has tripled over the past 20 years. However, effective treatments for MASLD and MASH other than diet, exercise, pioglitazone, and tocopherol nicotinate are lacking. This single-arm study investigated the effects of pemafibrate treatment on lipid levels, liver function, diabetes, and weight-related changes in patients with steatotic liver disease.

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Publication Details

Journal
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
Published
2025-01-01
DOI
https://doi.org/10.3999/jscpt.56.3_142
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Evaluation of Pemafibrate Treatment in Improving Liver Function and Lipid Profiles in Patients with Steatotic Liver Disease: Case Series Study

Yuma Tamura, Shinji Kitahama, Takanori Yasu, Susumu Ogawa et al.
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
Liver Disease Diagnosis and Treatment
article

Evaluation of Pemafibrate Treatment in Improving Liver Function and Lipid Profiles in Patients with Steatotic Liver Disease: Case Series Study

Yuma Tamura, Shinji Kitahama, Takanori Yasu, Susumu Ogawa, Tomoki Furuya
article en

Abstract

Background: The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) has tripled over the past 20 years. However, effective treatments for MASLD and MASH other than diet, exercise, pioglitazone, and tocopherol nicotinate are lacking. This single-arm study investigated the effects of pemafibrate treatment on lipid levels, liver function, diabetes, and weight-related changes in patients with steatotic liver disease.

Rinsho yakuri/Japanese Journal of Clinical Pharmacology and TherapeuticsVol. 56(3)
Tokyo Metropolitan Institute of Gerontology (JP), Dokkyo Medical University (JP)
Good health and well-being
Openalex Percentile: Top 82%
Liver Disease Diagnosis and Treatment
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