Imaging Amyloid-Beta Plaques in Brain Tissue Sections by Immunolabeling and Curcumin Staining

Source: Maiti, P. et. al.,. Labeling and Imaging of Amyloid Plaques in Brain Tissue Using the Natural Polyphenol Curcumin. J. Vis. Exp. (2019)This video demonstrates the imaging procedure of amyloid-beta plaques in brain tissue sections using immunolabeling and curcumin staining. Immunolabeling provides specificity for amyloid-beta, while curcumin selectively binds β-sheet-rich fibrils, enhancing visualization. The co-localization of red and green fluorescence confirms the presence of plaques.

Authors

Publication Details

Journal
Journal of Visualized Experiments
Published
2025-05-29
DOI
https://doi.org/10.3791/23462
Primary Topic
Supramolecular Self-Assembly in Materials
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Imaging Amyloid-Beta Plaques in Brain Tissue Sections by Immunolabeling and Curcumin Staining

TODO TODO
1 links
Journal of Visualized Experiments
Supramolecular Self-Assembly in Materials
article

Imaging Amyloid-Beta Plaques in Brain Tissue Sections by Immunolabeling and Curcumin Staining

TODO TODO
article en

Abstract

Source: Maiti, P. et. al.,. Labeling and Imaging of Amyloid Plaques in Brain Tissue Using the Natural Polyphenol Curcumin. J. Vis. Exp. (2019)This video demonstrates the imaging procedure of amyloid-beta plaques in brain tissue sections using immunolabeling and curcumin staining. Immunolabeling provides specificity for amyloid-beta, while curcumin selectively binds β-sheet-rich fibrils, enhancing visualization. The co-localization of red and green fluorescence confirms the presence of plaques.

Journal of Visualized Experiments
Zero hunger
Openalex Percentile: Top 93%
Supramolecular Self-Assembly in Materials
DOISourceOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Imaging Amyloid-Beta Plaques in Brain Tissue Sections by Immunolabeling and Curcumin Staining — TODO TODO · Journal of Visualized Experiments (2025) | TGRS Research Map | TGRS