Associations of volatile organic compounds with accelerated epigenetic aging in the lungs of smokers and electronic cigarette users
This is the first study reporting associations between smoking/EC-related VOCs and lung biological aging with strong associations in SM, supporting the need for further research on the roles of VOCs-related epigenetic aging and cell senescence genes in pulmonary diseases.
Authors
- Daniel Weng (ORCID: https://orcid.org/0000-0003-3903-9407)
- Min‐Ae Song (ORCID: https://orcid.org/0000-0002-2864-0224)
- Carson Richardson
- Sahar Kamel
- Amarnath Singh (ORCID: https://orcid.org/0000-0003-1762-6686)
- Sarah A. Reisinger (ORCID: https://orcid.org/0000-0002-3076-5405)
- Peter G. Shields (ORCID: https://orcid.org/0000-0002-7404-217X)
- Mark D. Wewers (ORCID: https://orcid.org/0000-0002-7079-5633)
- Ajmal Khan (ORCID: https://orcid.org/0000-0001-7851-6080)
- Joseph P. McElroy
Institutions
- The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (US)
- The Ohio State University Wexner Medical Center (US)
- The Ohio State University (US)
Publication Details
- Journal
- The Science of The Total Environment
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1016/j.scitotenv.2025.179792
- Citations
- 2
- Primary Topic
- Chemical Reactions and Isotopes
- Type
- article
- Field-Weighted Citation Impact
- 1.58
Funders
- U.S. Food and Drug Administration
- National Cancer Institute
- National Center for Advancing Translational Sciences