Tumor control and survival after postoperative radiotherapy for high-risk oral cavity cancer: A retrospective cohort study
A locoregional control of 84 % was achieved after PORT for high-risk OSCC with only 8 % receiving additional chemotherapy. Overall survival was 48 % at 8 years, with a large proportion of cancer-related deaths related to the index tumor and other subsequent tumor diagnoses. Risk of LF was increased for gingiva tumors with bone invasion. N1 stage was associated with a risk of solitary contralateral RFs in non-irradiated neck areas.
Authors
- Wilma D. Heemsbergen (ORCID: https://orcid.org/0000-0003-2144-0729)
- Joris B.W. Elbers (ORCID: https://orcid.org/0000-0003-1537-4139)
- Aniel Sewnaik
- Gerda M. Verduijn (ORCID: https://orcid.org/0000-0002-3513-6544)
- Brend P. Jonker (ORCID: https://orcid.org/0000-0003-0100-3871)
- Atilla Gül
- Pepijn B. Bolleurs
Institutions
- Elisabeth-TweeSteden Ziekenhuis (NL)
- Erasmus MC Cancer Institute (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1016/j.ctro.2025.100988
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00