Telmisartan-induced lichenoid drug eruption: a case report

Lichenoid drug eruption (LDE) is a rare adverse reaction to various medications, including antihypertensives like telmisartan. Early identification and withdrawal of the offending agent are key to management. A 52-year-old hypertensive male on telmisartan developed pruritic, violaceous lesions over the scalp and extremities, later spreading to the face, neck, and back, with oral involvement. Initial treatment offered partial relief. A diagnosis of telmisartan-induced lichenoid eruption was made, and the drug was replaced with amlodipine. Betamethasone mini-pulse therapy and azathioprine were initiated, leading to full resolution of lesions, leaving only post-inflammatory hyperpigmentation. Although uncommon, telmisartan can cause LDEs. Timely discontinuation and appropriate immunosuppressive therapy ensure favourable outcomes.

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Publication Details

Journal
International Journal of Research in Medical Sciences
Published
2025-05-30
DOI
https://doi.org/10.18203/2320-6012.ijrms20251662
Primary Topic
Oral Health Pathology and Treatment
Type
article
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article

Telmisartan-induced lichenoid drug eruption: a case report

Vishalkumar K. Vadgama, Jay Patel, Palak C. Sanghani, Trunali C. Navadiya
International Journal of Research in Medical Sciences
Oral Health Pathology and Treatment
article

Telmisartan-induced lichenoid drug eruption: a case report

Vishalkumar K. Vadgama, Jay Patel, Palak C. Sanghani, Trunali C. Navadiya
article en

Abstract

Lichenoid drug eruption (LDE) is a rare adverse reaction to various medications, including antihypertensives like telmisartan. Early identification and withdrawal of the offending agent are key to management. A 52-year-old hypertensive male on telmisartan developed pruritic, violaceous lesions over the scalp and extremities, later spreading to the face, neck, and back, with oral involvement. Initial treatment offered partial relief. A diagnosis of telmisartan-induced lichenoid eruption was made, and the drug was replaced with amlodipine. Betamethasone mini-pulse therapy and azathioprine were initiated, leading to full resolution of lesions, leaving only post-inflammatory hyperpigmentation. Although uncommon, telmisartan can cause LDEs. Timely discontinuation and appropriate immunosuppressive therapy ensure favourable outcomes.

International Journal of Research in Medical SciencesVol. 13(6)
Government Medical College Bhavnagar (IN), Government Medical College (IN)
Openalex Percentile: Top 87%
Oral Health Pathology and Treatment
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