Kinetics and Predictors of Hepatitis B Surface Antigen Loss After Commencing Hepatitis B Virus (HBV)–Active Antiretroviral Therapy in the Setting of HIV and Chronic HBV Coinfection
High HBsAg loss rates occur in PWH and HBV early after commencing ART. Our study suggests that TAF-containing ART regimens may be preferable as first-line therapy in HIV-HBV coinfection.
Authors
- Tim Spelman (ORCID: https://orcid.org/0000-0001-9204-3216)
- Sivaporn Gatechompol (ORCID: https://orcid.org/0000-0001-9511-370X)
- Olivia Maslac
- Anchalee Avihingsanon (ORCID: https://orcid.org/0000-0003-3222-9611)
- Peter Revill (ORCID: https://orcid.org/0000-0003-2715-2541)
- Hay Mar Su Lwin
- Iskandar Azwa (ORCID: https://orcid.org/0000-0003-1977-6709)
- Jennifer Audsley (ORCID: https://orcid.org/0000-0001-6322-3197)
- Sharon R. Lewin (ORCID: https://orcid.org/0000-0002-0330-8241)
- Nadia Warner (ORCID: https://orcid.org/0000-0002-4252-086X)
- Joe Sasadeusz (ORCID: https://orcid.org/0000-0001-7438-0382)
- Kathy Merlock Jackson (ORCID: https://orcid.org/0000-0002-0507-678X)
- Xin Li (ORCID: https://orcid.org/0000-0001-8948-6331)
- Nagalingeswaran Kumarasamy
- Adeeba Kamarulzaman
- Rosalind Edwards (ORCID: https://orcid.org/0000-0002-4976-2562)
Institutions
- The Royal Melbourne Hospital (AU)
- Burnet Institute (AU)
- The University of Melbourne (AU)
- Voluntary Health Services Hospital (IN)
- Karolinska Institutet (SE)
- University of Malaya (MY)
- Victorian Infectious Diseases Reference Laboratory (AU)
- Peter Doherty Institute (AU)
- HIV Netherlands Australia Thailand Research Collaboration (TH)
- Monash University (AU)
- The University of Adelaide (AU)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1093/cid/ciaf281
- Citations
- 5
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 6.77
Funders
- National Health and Medical Research Council