Impact of Hemoglobin–Albumin–Lymphocyte–Platelet (HALP) Score on Mortality in Above-Ankle Amputation of Diabetic Foot Infection

Background and Purpose: :Diabetic foot ulcers are one of the important reasons for amputations The hemoglobin–albumin–lymphocyte–platelet (HALP) score is a marker of the inflammatory and nutritional status of the individual. Aim of this study is to investigate the relationship between the HALP score and mortality in patients undergoing above-ankle amputation due to diabetic foot infection. Methods: The demographic data (age, sex), deaths during hospitalization, laboratory values and mortality through 3-6-9-12 months were recorded. Chi square and t test were used for categorical comparation and logistic regression tests were used for mortality risk estimation. Results:. The mortality rates in hospital and in the 3rd, 6th, 9th, and 12th months were 13.1%, 37.7%, 48.5%, 53.8%, and 56.2%. HALP score below 21.55 had a 1-year mortality risk that was 2.975 times than that of score above 21.55 (odds ratio=2.975, 95% CI [1.252-7.069]; p=0.014). Female gender and a HALP score of less than 21.55 and older age than 65 estimates a 20.2% overall 1-year mortality risk (Nagelkerke R square: 0.202). Conclusion: The HALP score is an essential predictor of prognosis in patients undergoing amputation for diabetic foot ulcers. Also; older age and female gender are independent risk factors for 1-year mortality.