Impactos da fração inspirada de oxigênio e o desfecho clínico de pacientes COVID-19 em ventilação mecânica

Objective: to evaluate the correlation between the average FiO2 and the outcome of these patients admitted to the Covid-19 ICU, as well as to analyze the time spent on ventilation, gender, age and days of hospitalization. Method: Retrospective, quantitative cohort, with patients with Covid-19 admitted to the intensive care unit of a University Hospital in Paraná-Brazil, from April 2020 to April 2021. Results: From the total sample (n=625) , the prevalence of deaths was 73.12%, mean age 61.18 years. The average time on mechanical ventilation was 11.97 days and the average FiO2 was 52.53%. FiO2 > 60% was associated with a higher risk of death (52%). Age over 45 years was associated with a higher risk of death. A lower risk of death was identified for prolonged days of hospitalization and MV. Conclusion: Excessive use of oxygen is a risk factor for worse outcomes. Age was not a predictor of higher FiO2 and effective weaning was shown to be a protective factor against high oxygen concentrations.