Bioluminescence Imaging in an EAE Mouse Model

Source: Schmitz, K., et al., Bioluminescence and Near-infrared Imaging of Optic Neuritis and Brain Inflammation in the EAE Model of Multiple Sclerosis in Mice. J. Vis. Exp. (2017).This video demonstrates the method for visualizing and monitoring Experimental Autoimmune Encephalomyelitis or EAE-induced inflammation in the optic nerve using bioluminescence imaging. It includes positioning the mouse, reagent injection, and capturing sequential images to monitor changes in bioluminescence over time.

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Publication Details

Journal
Journal of Visualized Experiments
Published
2025-05-29
DOI
https://doi.org/10.3791/23514
Primary Topic
bioluminescence and chemiluminescence research
Type
article
Field-Weighted Citation Impact
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article

Bioluminescence Imaging in an EAE Mouse Model

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Journal of Visualized Experiments
bioluminescence and chemiluminescence research
article

Bioluminescence Imaging in an EAE Mouse Model

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article en

Abstract

Source: Schmitz, K., et al., Bioluminescence and Near-infrared Imaging of Optic Neuritis and Brain Inflammation in the EAE Model of Multiple Sclerosis in Mice. J. Vis. Exp. (2017).This video demonstrates the method for visualizing and monitoring Experimental Autoimmune Encephalomyelitis or EAE-induced inflammation in the optic nerve using bioluminescence imaging. It includes positioning the mouse, reagent injection, and capturing sequential images to monitor changes in bioluminescence over time.

Journal of Visualized Experiments
Openalex Percentile: Top 89%
bioluminescence and chemiluminescence research
DOISourceOpenAlex
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