Fluorescence Photoactivation Imaging of Neurofilament Transport in Myelinated Mouse Axons

Source: Boyer, N. P. et. al., Imaging and Analysis of Neurofilament Transport in Excised Mouse Tibial Nerve. J. Vis. Exp. (2020) This video demonstrates the fluorescence photoactivation method to analyze neurofilament transport in myelinated axons of peripheral nerves. By tracking photoactivated green fluorophore-tagged neurofilaments, the technique provides insights into axonal transport in neurodegenerative diseases.

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Publication Details

Journal
Journal of Visualized Experiments
Published
2025-05-29
DOI
https://doi.org/10.3791/23540
Primary Topic
Skin and Cellular Biology Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Fluorescence Photoactivation Imaging of Neurofilament Transport in Myelinated Mouse Axons

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Journal of Visualized Experiments
Skin and Cellular Biology Research
article

Fluorescence Photoactivation Imaging of Neurofilament Transport in Myelinated Mouse Axons

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Abstract

Source: Boyer, N. P. et. al., Imaging and Analysis of Neurofilament Transport in Excised Mouse Tibial Nerve. J. Vis. Exp. (2020) This video demonstrates the fluorescence photoactivation method to analyze neurofilament transport in myelinated axons of peripheral nerves. By tracking photoactivated green fluorophore-tagged neurofilaments, the technique provides insights into axonal transport in neurodegenerative diseases.

Journal of Visualized Experiments
Openalex Percentile: Top 87%
Skin and Cellular Biology Research
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