High concordance between Immunohistochemistry and RT-PCR in diagnosing ALK rearrangement in lung adenocarcinoma cytologic samples.

The high concordance between IHC and qRTPCR underscores their reliability in detecting ALK rearrangements, crucial for the precise diagnosis and treatment of lung adenocarcinoma in Indonesia. These findings support the use of either method, depending on available resources and expertise, to enhance lung cancer management.

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Journal
PubMed
Published
2025-05-01
Primary Topic
Lung Cancer Treatments and Mutations
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article
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article

High concordance between Immunohistochemistry and RT-PCR in diagnosing ALK rearrangement in lung adenocarcinoma cytologic samples.

Haryo Aribowo, VENG-KIN LAU, Yunanto Kurnia, Indah Trisnawati et al.
PubMed
Lung Cancer Treatments and Mutations
article

High concordance between Immunohistochemistry and RT-PCR in diagnosing ALK rearrangement in lung adenocarcinoma cytologic samples.

Haryo Aribowo, VENG-KIN LAU, Yunanto Kurnia, Indah Trisnawati, Andrew Nobiantoro Gunawan, Hsiao‐Chi Chuang, Jeffry Beta Tenggara, Didik Setyo Heriyanto, Vincent Laiman, Fara Silvia Yuliani, Rita Cempaka, Lisnawati Rachmadi, Brigitta Natasya Halim
article en

Abstract

The high concordance between IHC and qRTPCR underscores their reliability in detecting ALK rearrangements, crucial for the precise diagnosis and treatment of lung adenocarcinoma in Indonesia. These findings support the use of either method, depending on available resources and expertise, to enhance lung cancer management.

PubMedVol. 80(3)
Universitas Gadjah Mada (ID), Siloam Eye Hospital (KR), Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo (ID), Rumah Sakit Umum Pusat Dr. Sardjito (ID), Taipei Medical University (TW)
Openalex Percentile: Top 80%
Lung Cancer Treatments and Mutations
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High concordance between Immunohistochemistry and RT-PCR in diagnosing ALK rearrangement in lung adenocarcinoma cytologic samples. — Haryo Aribowo, VENG-KIN LAU, et al. · PubMed (2025) | TGRS Research Map | TGRS