Risks of extracolonic tumours in patients with Lynch syndrome: a nationwide multicentre cohort study in Japan

This study highlights the need for tailored surveillance programmes based on cancer type, sex, causative pathogenic genetic variants, and risk profiles to effectively manage LS in Japan.

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Publication Details

Journal
Japanese Journal of Clinical Oncology
Published
2025-05-09
DOI
https://doi.org/10.1093/jjco/hyaf087
Primary Topic
Genetic factors in colorectal cancer
Type
article
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0.00
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article

Risks of extracolonic tumours in patients with Lynch syndrome: a nationwide multicentre cohort study in Japan

Gou Yamamoto, Takeshi Nakajima, Masayoshi Yamada, Naohiro Tomita et al.
Japanese Journal of Clinical Oncology
Genetic factors in colorectal cancer
article

Risks of extracolonic tumours in patients with Lynch syndrome: a nationwide multicentre cohort study in Japan

Gou Yamamoto, Takeshi Nakajima, Masayoshi Yamada, Naohiro Tomita, Kiwamu Akagi, Kohji Tanakaya, Eiki Miyake, Mai Ego, Tatsuro Yamaguchi, Masashi Miguchi, Akinari Takao, Yoichi Ajioka, Arisa Ueki, Tatsuki Noguchi, Hideyuki Ishida, Akiko Chino, Keiji Hirata, Misato Takao, Yoshiko Mori, Fumitaka Taniguchi
article en

Abstract

This study highlights the need for tailored surveillance programmes based on cancer type, sex, causative pathogenic genetic variants, and risk profiles to effectively manage LS in Japan.

Japanese Journal of Clinical OncologyVol. 55(9)
University of Occupational and Environmental Health Japan (JP), Saitama Prefecture (JP), Tokyo Metropolitan Komagome Hospital (JP), Toyonaka Municipal Hospital (JP), National Cancer Center (US), Hiroshima Prefectural Hospital (JP), Saitama Cancer Center (JP), Iwakuni Medical Center (JP), Osaka International Cancer Institute (JP), Social Insurance Saitama Chuo Hospital (JP), Japanese Foundation For Cancer Research (JP), Niigata University (JP), Saitama Medical University (JP)
Good health and well-being
Openalex Percentile: Top 83%
Genetic factors in colorectal cancer
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