Establishment and validation of downsized hollow-fibre infection model and pharmacokinetics/pharmacodynamics analysis of VAN on <i>Enterococcus faecium</i>
We established a downsized HFIM and demonstrated its viability as a cost-effective and environmentally sustainable in vitro PK/PD. The findings highlighted its potential as a future PK/PD analysis standard.
Authors
- Yuki Enoki (ORCID: https://orcid.org/0000-0002-5934-0670)
- Michiko Takahashi (ORCID: https://orcid.org/0000-0002-5422-2990)
- Kazuaki Matsumoto (ORCID: https://orcid.org/0000-0002-5462-1684)
- Moe Sasaki
- Kazuaki Taguchi (ORCID: https://orcid.org/0000-0002-3575-0448)
- Tetsuo Yamaguchi (ORCID: https://orcid.org/0000-0002-6220-1890)
- Xiaoxi Liu (ORCID: https://orcid.org/0000-0002-1933-8613)
- Kenta Suzuki (ORCID: https://orcid.org/0000-0001-6525-4704)
- Yukitaka Hayashi
- Yuki Mizukami
- Tateda Kazuhiro
Institutions
- Toho University (JP)
- Keio University (JP)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1093/jac/dkaf175
- Citations
- 1
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 1.40