Operation Alone for Resectable Pancreatic Adenocarcinoma: Should We Operate if Multimodal Treatment Is Off the Table?

This national study of patients with early-stage PDAC affirms that surgical resection, in the absence of multimodal therapy, is associated with improved outcomes compared with no resection. However, the association with improved survival is clinically annulled in the absence of a negative-margin resection.

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Publication Details

Journal
Journal of the American College of Surgeons
Published
2025-05-30
DOI
https://doi.org/10.1097/xcs.0000000000001464
Citations
1
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
Field-Weighted Citation Impact
1.05
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article

Operation Alone for Resectable Pancreatic Adenocarcinoma: Should We Operate if Multimodal Treatment Is Off the Table?

Peter J. Fagenholz, Carlos F. Fernandez-del Castillo, Motaz Qadan, Keith D. Lillemoe et al.
1 citations
Journal of the American College of Surgeons
Pancreatic and Hepatic Oncology Research
1.05
article

Operation Alone for Resectable Pancreatic Adenocarcinoma: Should We Operate if Multimodal Treatment Is Off the Table?

Peter J. Fagenholz, Carlos F. Fernandez-del Castillo, Motaz Qadan, Keith D. Lillemoe, Roi Anteby, William V. Kastrinakis
article en
1 citations

Abstract

This national study of patients with early-stage PDAC affirms that surgical resection, in the absence of multimodal therapy, is associated with improved outcomes compared with no resection. However, the association with improved survival is clinically annulled in the absence of a negative-margin resection.

Journal of the American College of SurgeonsVol. 241(5)
Newton Wellesley Hospital (US), Salem Hospital (US), Massachusetts General Hospital (US)
Good health and well-being
Openalex Percentile: Top 21%
Pancreatic and Hepatic Oncology Research
1.05
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Operation Alone for Resectable Pancreatic Adenocarcinoma: Should We Operate if Multimodal Treatment Is Off the Table? — Peter J. Fagenholz, Carlos F. Fernandez-del Castillo, et al. · Journal of the American College of Surgeons (2025) | TGRS Research Map | TGRS