Helicobacter pylori is associated with less tumor-infiltrating lymphocytes and a poor prognosis in gastric cancer
Our study supports the hypothesis that H. pylori infection was positively correlated with less TILs and CD8<sup>+</sup>TILs, which may contribute to anti-tumor immune escape, thus lead to a poor prognosis of GC.
Authors
- Hongda Liu (ORCID: https://orcid.org/0000-0002-5977-9130)
- Qingya Li (ORCID: https://orcid.org/0000-0003-0094-6456)
- Zetian Chen
- Sen Wang (ORCID: https://orcid.org/0000-0003-1259-8030)
- Zekuan Xu (ORCID: https://orcid.org/0000-0001-5179-4128)
- Zhijun Zhang (ORCID: https://orcid.org/0000-0001-6916-2356)
- Zhizhong Li (ORCID: https://orcid.org/0000-0002-9571-9311)
- Chengjun Zhu (ORCID: https://orcid.org/0000-0002-4642-4920)
- Lü Chen (ORCID: https://orcid.org/0000-0001-5527-7881)
- Hongxin Huang (ORCID: https://orcid.org/0009-0006-8313-585X)
- Mengpei Yan
Institutions
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1186/s12876-025-04003-w
- Citations
- 1
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Natural Science Foundation of Jiangsu Province
- Nanjing Medical University
- Priority Academic Program Development of Jiangsu Higher Education Institutions