Age-dependent nonlinear relationship between hypertension and hippocampal volume in sedentary women with lower educational attainment
These findings challenge the "lower is better" blood pressure paradigm, especially in older adults, suggesting the need for age-specific hypertension management and brain health preservation strategies. Public health implications include developing tailored interventions considering age, education, and physical activity; implementing age-specific blood pressure guidelines; integrating cognitive screenings into hypertension care; and creating targeted health literacy programs. Future research should establish causality, explore mechanisms, and evaluate personalized strategies for this vulnerable population.
Authors
- Sneha Ravichandran (ORCID: https://orcid.org/0000-0002-4421-038X)
- Suresh Sukumar (ORCID: https://orcid.org/0000-0001-9345-9790)
- Baskaran Chandrasekaran (ORCID: https://orcid.org/0000-0003-1439-9158)
- Winniecia Dkhar (ORCID: https://orcid.org/0000-0001-5963-3230)
- Rajagopal Kadavigere (ORCID: https://orcid.org/0000-0003-3486-8740)
- M. G. Ramesh Babu
- Dilip Shettigar
- Hari Prakash Palaniswamy (ORCID: https://orcid.org/0000-0002-5631-9411)
- K N Shivashankar
- Sathya Sabina Muthu
- Poovitha Shruthi Paramashiva (ORCID: https://orcid.org/0000-0002-6267-7266)
Institutions
- Manipal Academy of Higher Education (IN)
- Kasturba Medical College, Manipal (IN)
Publication Details
- Journal
- Journal of Education and Health Promotion
- Published
- 2025-05-01
- DOI
- https://doi.org/10.4103/jehp.jehp_1219_24
- Primary Topic
- Cardiovascular Health and Disease Prevention
- Type
- article
- Field-Weighted Citation Impact
- 0.00