Application and Feasibility Analysis of the Method of Calculating and Dynamically Adjusting AUD in a Hospital

目的：探寻一种合理准确、简便可行的计算方法制定不同临床科室AUD目标值，并为动态评价管理不同科室抗菌药物使用情况提供依据。方法：通过分析AUD的计算公式，推导出AUD的关键影响因素为抗菌药物使用率和患者抗菌药物使用总天数(每种抗菌药物使用总天数之和)，根据两者的影响因素(抗菌药物的使用率、使用疗程、微生物检出率、出院患者感染诊断率、联合用药率等)，通过某医院信息系统导出相关数据，计算得出临床科室AUD目标值，并通过定时核查、动态评价、与临床沟通等及时管理某医院临床科室抗菌药物的不合理使用情况。结果：通过数据计算的方法制定新的AUD指标更有说服力，临床科室易于接受，并可通过动态分析调整AUD目标，及时发现临床科室抗菌药物使用过程中存在的问题，并及时解决，保证医院抗菌药物合理使用。结论：利用科室抗菌药物使用率和患者一种或多种抗菌药物使用总天数的相关影响因素制定临床科室AUD目标值科学合理，能反映临床科室合理应用抗菌药物的特点，简单宜行，可以作为制定和控制不同科室AUD的一种方法。Objective: To explore a reasonable, accurate, simple and feasible calculation method to establish AUD target values for different clinical departments, and to provide a basis for dynamic evaluation and management of antibacterial drug use in different departments. Methods: By analyzing the calculation formula of AUD, it was derived that the key influencing factors of AUD are the usage rate of antimicrobial drugs and the total number of patient days of antimicrobial use (the sum of the total days of use for each antimicrobial drug). Based on these factors, including the usage rate of antimicrobial drugs, duration of use, microbiological detection rate, infection diagnosis rate of discharged patients, and combined medication rate, relevant data were exported from the information system of a certain hospital. The target value of AUD for clinical departments was calculated, and through regular checks, dynamic evaluations, and communication with clinical staff, the irrational use of antimicrobial drugs in clinical departments was managed in a timely manner. Result: Formulating new AUD indicators through data calculation is more persuasive and easily accepted by clinical departments. The AUD targets can be adjusted through dynamic analysis, allowing for the timely identification and resolution of issues in the use of antimicrobial drugs in clinical departments, thereby ensuring their rational use in the hospital. Conclusion: Setting the target value of AUD for clinical departments based on the usage rate of antimicrobial drugs and the total number of days of use for one or more antimicrobial drugs is scientific and reasonable. This approach reflects the characteristics of rational antimicrobial drug use in clinical departments, is simple and feasible, and can serve as a method for setting and controlling AUD in different departments.