Differences in Parkinson's Disease Populations: Teaching Hospitals Versus Other Settings and Implications for Clinical Trials
Individuals with PD seen early by teaching hospital neurologists exhibited differences from the PD population. DMT trials in PD may exclude individuals with faster PD progression and from marginalized groups, impacting generalizability. Our study highlights health equity issues. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Authors
- Abby Emdin (ORCID: https://orcid.org/0009-0002-0640-7365)
- Michael E. Farkouh (ORCID: https://orcid.org/0000-0002-8095-0246)
- Priti Gros (ORCID: https://orcid.org/0000-0001-8250-5915)
- Connie Marras (ORCID: https://orcid.org/0000-0002-9236-9328)
- Susan E. Bronskill (ORCID: https://orcid.org/0000-0002-7341-0655)
- Maria Chiu (ORCID: https://orcid.org/0000-0002-3877-1068)
- Xuesong Wang (ORCID: https://orcid.org/0000-0003-3259-1880)
Institutions
- Sunnybrook Health Science Centre (CA)
- University Health Network (CA)
- Pediatric Oncology Group (CA)
- University of Toronto (CA)
- Toronto Western Hospital (CA)
- Health Sciences Centre (CA)
- Public Health Ontario (CA)
- Institute for Clinical Evaluative Sciences (CA)
- Sinai Health System (US)
- Sunnybrook Research Institute
Publication Details
- Journal
- Movement Disorders
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1002/mds.30239
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Michael J. Fox Foundation for Parkinson's Research
- Parkinson's Foundation
- Alzheimer Society
- Novo Nordisk
- Parkinson Canada
- Canadian Institutes of Health Research