Clinical features and mutational frequency of renal cell carcinoma from patients undergoing kidney transplant evaluation
This study identifies key mutations in RCC among patients with CKD and post-kidney transplant, highlighting a complex relationship between renal dysfunction, inflammation, and tumorigenesis. Despite its limited sample size, the findings underscore the need for further research to understand the molecular drivers of RCC in high-risk populations, which could lead to more personalized treatment strategies.
Authors
- Junxiao Hu (ORCID: https://orcid.org/0000-0002-5937-7916)
- Kurtis D. Davies (ORCID: https://orcid.org/0000-0002-1532-6308)
- Alkesh Jani (ORCID: https://orcid.org/0000-0003-4538-5509)
- Elaine T. Lam (ORCID: https://orcid.org/0000-0001-5629-3402)
- Corbin Eule (ORCID: https://orcid.org/0000-0002-8430-1040)
- Thomas Pshak (ORCID: https://orcid.org/0000-0001-7584-7108)
Institutions
- University of Colorado Cancer Center (US)
- Rocky Mountain MS Center (US)
- University of Colorado Anschutz Medical Campus (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-05-29
- DOI
- https://doi.org/10.3389/fonc.2025.1526545
- Citations
- 1
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Cancer Center, University of Colorado