The threshold effect of fasting blood glucose levels on the risk of delivering macrosomia in gestational diabetes mellitus patients
There is a nonlinear relationship between FBG levels during pregnancy and the risk of macrosomia in GDM women, with a potential threshold effect at 8.037 mmol/L. Below the threshold, macrosomia prevalence markedly rises with elevated FBG levels, whereas above it, the association loses significance, implying a potential saturation at very high glucose levels.
Authors
- Wenjun Zheng (ORCID: https://orcid.org/0000-0002-0357-9279)
- Ruili Huang (ORCID: https://orcid.org/0000-0001-8886-8311)
- Yumei Gao (ORCID: https://orcid.org/0000-0001-6784-8493)
- Ying Chen (ORCID: https://orcid.org/0000-0002-5919-743X)
- Yuan Li (ORCID: https://orcid.org/0000-0003-0438-7794)
- Tingting Yang (ORCID: https://orcid.org/0000-0002-2968-7702)
- Yumin Zhu
Institutions
- Xuzhou Medical College (CN)
- Shangqiu First People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-05-29
- DOI
- https://doi.org/10.3389/fendo.2025.1587306
- Citations
- 1
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 2.06
Funders
- National Natural Science Foundation of China