Obesity-related alterations of intrinsic functional architecture: a resting-state fMRI study based on the human connectome project
Together our findings suggested that obesity is associated with atypical neurotransmitter systems and dysfunctional architecture especially in the prefrontal cortex, insula, sensorimotor cortex, and default mode circuits. These may deepen our understanding the neurobiological basis of obesity and provide novel insights into neuroimaging-based treatment and intervention.
Authors
- Shuaiyu Chen (ORCID: https://orcid.org/0000-0002-4822-6995)
- Yan Jin (ORCID: https://orcid.org/0000-0001-7749-7367)
- Qian Zhuang
- Matthew Lock
- Todd Jackson (ORCID: https://orcid.org/0000-0001-5086-7663)
- Tongtong Wang (ORCID: https://orcid.org/0000-0002-0408-2571)
- Hui Li (ORCID: https://orcid.org/0000-0002-1973-3074)
Institutions
- University of Macau (MO)
- Affiliated Hospital of Hangzhou Normal University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-05-29
- DOI
- https://doi.org/10.3389/fnut.2025.1559325
- Citations
- 3
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.29
Funders
- National Natural Science Foundation of China
- National Institutes of Health
- McDonnell Center for Systems Neuroscience
- Natural Science Foundation of Zhejiang Province