Primary cardiac angiosarcoma: a case report

Primary cardiac tumors are extremely rare, with an incidence rate ranging from only 0.17% to 0.33%. Clinically, their diagnosis is often delayed due to nonspecific clinical symptoms. This paper reports a case of primary cardiac angiosarcoma (PCAS) pathologically confirmed via surgery, presenting with recurrent palpitations during exertion as the initial symptom. The patient subsequently developed bilateral lung and liver metastases and received chemotherapy. Through a comprehensive review of the literature, this report explores the diagnostic and therapeutic strategies for PCAS, with a focus on analyzing the mechanisms underlying the atypical disease course, the rationale for treatment decisions, and the key clinical insights.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-05-29
DOI
https://doi.org/10.3389/fonc.2025.1575207
Citations
2
Primary Topic
Cardiac tumors and thrombi
Type
article
Field-Weighted Citation Impact
2.78
Controls
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article

Primary cardiac angiosarcoma: a case report

Gengming Wang, Wenjie Diao, Yu Zhao, Yuan Yin et al.
2 citations
Frontiers in Oncology
Cardiac tumors and thrombi
2.78
article

Primary cardiac angiosarcoma: a case report

Gengming Wang, Wenjie Diao, Yu Zhao, Yuan Yin, Zelai He, Jianming Ding
article en
2 citations

Abstract

Primary cardiac tumors are extremely rare, with an incidence rate ranging from only 0.17% to 0.33%. Clinically, their diagnosis is often delayed due to nonspecific clinical symptoms. This paper reports a case of primary cardiac angiosarcoma (PCAS) pathologically confirmed via surgery, presenting with recurrent palpitations during exertion as the initial symptom. The patient subsequently developed bilateral lung and liver metastases and received chemotherapy. Through a comprehensive review of the literature, this report explores the diagnostic and therapeutic strategies for PCAS, with a focus on analyzing the mechanisms underlying the atypical disease course, the rationale for treatment decisions, and the key clinical insights.

Frontiers in OncologyVol. 15
Bengbu Medical College (CN), First Affiliated Hospital of Bengbu Medical College (CN)
Good health and well-being
Openalex Percentile: Top 10%
Cardiac tumors and thrombi
2.78
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