Fertility-sparing surgery in primary peritoneal serous borderline tumor: a case report

Primary peritoneal serous borderline tumor (PPSBT) is a rare, low-malignant-potential neoplasm arising from the peritoneum, diagnosed only after excluding ovarian involvement. While typically discovered incidentally during surgery, it often presents with infertility or abdominal pain in young women. Due to its favorable prognosis and the desire to preserve fertility, fertility-sparing surgery (FSS) is a critical consideration. We report a case of PPSBT in a reproductive-aged woman who underwent three FSS procedures, demonstrating the feasibility of this approach. Our findings support FSS as a viable option for PPSBT patients after thorough exclusion of ovarian malignancy. This case underscores the importance of comprehensive surgical staging and multidisciplinary evaluation to optimize oncological and reproductive outcomes. Further research is needed to standardize management strategies for this rare condition.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-05-29
DOI
https://doi.org/10.3389/fonc.2025.1480730
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
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article

Fertility-sparing surgery in primary peritoneal serous borderline tumor: a case report

Tingting Li, Wei Jiang, Hongjing Wang
Frontiers in Oncology
Ovarian cancer diagnosis and treatment
article

Fertility-sparing surgery in primary peritoneal serous borderline tumor: a case report

Tingting Li, Wei Jiang, Hongjing Wang
article en

Abstract

Primary peritoneal serous borderline tumor (PPSBT) is a rare, low-malignant-potential neoplasm arising from the peritoneum, diagnosed only after excluding ovarian involvement. While typically discovered incidentally during surgery, it often presents with infertility or abdominal pain in young women. Due to its favorable prognosis and the desire to preserve fertility, fertility-sparing surgery (FSS) is a critical consideration. We report a case of PPSBT in a reproductive-aged woman who underwent three FSS procedures, demonstrating the feasibility of this approach. Our findings support FSS as a viable option for PPSBT patients after thorough exclusion of ovarian malignancy. This case underscores the importance of comprehensive surgical staging and multidisciplinary evaluation to optimize oncological and reproductive outcomes. Further research is needed to standardize management strategies for this rare condition.

Frontiers in OncologyVol. 15
Sichuan University (CN), West China Second University Hospital of Sichuan University (CN)
Gender equality
Openalex Percentile: Top 83%
Ovarian cancer diagnosis and treatment
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