Association between the ratio of triglycerides to high-density lipoprotein cholesterol and nocturnal hypertension: a cross-sectional study in a Chinese population
Our study underscores the significant association between an elevated TG/HDL-C ratio and the occurrence of nocturnal hypertension. This finding has the potential to draw the attention of patients and physicians to lipid levels, particularly among males, individuals over 45 years old, those with a BMI greater than 24, smokers, and those with a history of hypertension. An independent positive association between TG/HDL-C and nocturnal hypertension was also determined using logistic regression modeling. The findings suggests that it may have potential application in the early screening of nocturnal hypertension. However, the predictive ability is limited, and further studies are necessary to incorporate larger sample sizes and longitudinal designs. These additional studies would validate the predictive role of TG/HDL-C and explore its biological mechanisms.
Authors
- Zhaozheng Liu
- Liping Chang (ORCID: https://orcid.org/0000-0001-6089-6767)
- Yue Deng (ORCID: https://orcid.org/0000-0001-8874-911X)
- Hezeng Dong (ORCID: https://orcid.org/0000-0001-5018-8900)
- Xi Yang (ORCID: https://orcid.org/0000-0002-5691-1888)
- Jing Zhang (ORCID: https://orcid.org/0000-0001-8861-7336)
- Jinling Zhang (ORCID: https://orcid.org/0000-0003-0482-5432)
- Ye Han (ORCID: https://orcid.org/0000-0003-2644-9431)
Institutions
- Changchun University of Chinese Medicine (CN)
- The Affiliated Hospital to Changchun University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-05-29
- DOI
- https://doi.org/10.3389/fendo.2025.1474467
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00