Association between the ratio of triglycerides to high-density lipoprotein cholesterol and nocturnal hypertension: a cross-sectional study in a Chinese population

Our study underscores the significant association between an elevated TG/HDL-C ratio and the occurrence of nocturnal hypertension. This finding has the potential to draw the attention of patients and physicians to lipid levels, particularly among males, individuals over 45 years old, those with a BMI greater than 24, smokers, and those with a history of hypertension. An independent positive association between TG/HDL-C and nocturnal hypertension was also determined using logistic regression modeling. The findings suggests that it may have potential application in the early screening of nocturnal hypertension. However, the predictive ability is limited, and further studies are necessary to incorporate larger sample sizes and longitudinal designs. These additional studies would validate the predictive role of TG/HDL-C and explore its biological mechanisms.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-05-29
DOI
https://doi.org/10.3389/fendo.2025.1474467
Primary Topic
Blood Pressure and Hypertension Studies
Type
article
Field-Weighted Citation Impact
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article

Association between the ratio of triglycerides to high-density lipoprotein cholesterol and nocturnal hypertension: a cross-sectional study in a Chinese population

Zhaozheng Liu, Liping Chang, Yue Deng, Hezeng Dong et al.
Frontiers in Endocrinology
Blood Pressure and Hypertension Studies
article

Association between the ratio of triglycerides to high-density lipoprotein cholesterol and nocturnal hypertension: a cross-sectional study in a Chinese population

Zhaozheng Liu, Liping Chang, Yue Deng, Hezeng Dong, Xi Yang, Jing Zhang, Jinling Zhang, Ye Han
article en

Abstract

Our study underscores the significant association between an elevated TG/HDL-C ratio and the occurrence of nocturnal hypertension. This finding has the potential to draw the attention of patients and physicians to lipid levels, particularly among males, individuals over 45 years old, those with a BMI greater than 24, smokers, and those with a history of hypertension. An independent positive association between TG/HDL-C and nocturnal hypertension was also determined using logistic regression modeling. The findings suggests that it may have potential application in the early screening of nocturnal hypertension. However, the predictive ability is limited, and further studies are necessary to incorporate larger sample sizes and longitudinal designs. These additional studies would validate the predictive role of TG/HDL-C and explore its biological mechanisms.

Frontiers in EndocrinologyVol. 16
Changchun University of Chinese Medicine (CN), The Affiliated Hospital to Changchun University of Chinese Medicine (CN)
Openalex Percentile: Top 78%
Blood Pressure and Hypertension Studies
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Association between the ratio of triglycerides to high-density lipoprotein cholesterol and nocturnal hypertension: a cross-sectional study in a Chinese population — Zhaozheng Liu, Liping Chang, et al. · Frontiers in Endocrinology (2025) | TGRS Research Map | TGRS