Molecular targets and mechanisms of cortex mori for lung cancer treatment: a network pharmacology study, molecular docking and in vitro and in vivo experimental validation
Cortex mori acts on AKT and other related disease targets of lung cancer cells through effective components such as cyclomolorusin, and plays a role in the treatment of lung cancer by inhibiting the signaling pathway associated with lung cancer occurrence and development.
Authors
- Rong‐Rong He (ORCID: https://orcid.org/0000-0001-5505-5672)
- Baocheng Xie (ORCID: https://orcid.org/0000-0002-7109-402X)
- Han-Bin Zhang
- Qiu-Hong Yang
- Weichao Han (ORCID: https://orcid.org/0000-0002-1866-9891)
- Shu-Fen He
- Yingying Shao (ORCID: https://orcid.org/0000-0003-0278-5182)
- Wenxin Hong
Institutions
- Zunyi Medical University (CN)
- Dongguan People’s Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-05-29
- DOI
- https://doi.org/10.3389/fonc.2025.1587856
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00