Weight-adjusted waist index is associated with risk of poor bone quality rather than low bone mass in patients with type 2 diabetes
Our findings highlight WWI as a novel and potentially more precise indicator of body fat, associated with diminished bone quality rather than solely low bone mass in patients with T2D in China. These results suggest that evaluating bone health in individuals with higher WWI may require more than just bone mass assessment. The results also suggest that the optimal WWI cut-off points for predicting degraded TBS are approximately 11.25 cm/√kg, highlighting thresholds for fracture risk.
Authors
- Shujuan Chen (ORCID: https://orcid.org/0000-0001-6829-6547)
- Dewen Yan (ORCID: https://orcid.org/0000-0003-4998-2853)
- Junying Liu (ORCID: https://orcid.org/0000-0002-6924-9432)
- Ningning Bai (ORCID: https://orcid.org/0009-0009-0002-3230)
- Shaobin Wang (ORCID: https://orcid.org/0000-0002-0377-2095)
- Dehuai Feng
- Zhiming Cai (ORCID: https://orcid.org/0009-0006-4307-8272)
- Liming Zhou (ORCID: https://orcid.org/0000-0002-7416-2913)
- Sheng Ouyang (ORCID: https://orcid.org/0000-0001-8887-1991)
- Ling Chen (ORCID: https://orcid.org/0000-0003-3187-8759)
- Yiting Zheng (ORCID: https://orcid.org/0000-0003-2351-6707)
- Keli Zhao (ORCID: https://orcid.org/0000-0002-1596-1336)
- Jie Wan (ORCID: https://orcid.org/0000-0003-1539-3284)
- Xinlian He
Institutions
- Peking University Shenzhen Hospital (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1186/s13098-025-01740-6
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation