Harnessing NKG2D CAR-T cells with radiotherapy: a novel approach for esophageal squamous cell carcinoma treatment
We first clarified the therapeutic efficacy of NKG2D CAR-T cells in ESCC, as well as their enhanced effect when combined with radiotherapy, which provides a novel treatment strategy for ESCC patients.
Authors
- Pengxiang Chen (ORCID: https://orcid.org/0000-0002-7660-4981)
- Kaiyue Guo
- Wei‐Cheng Huang (ORCID: https://orcid.org/0000-0003-4437-3530)
- Yali Han (ORCID: https://orcid.org/0000-0003-4533-922X)
- Yuchen Liu (ORCID: https://orcid.org/0000-0003-2698-3482)
- Tianyu Liu (ORCID: https://orcid.org/0000-0003-3735-3814)
- Liyuan Fan (ORCID: https://orcid.org/0000-0002-9520-8482)
- Yufeng Cheng (ORCID: https://orcid.org/0000-0001-8342-5802)
- Shuyun Wang (ORCID: https://orcid.org/0009-0000-2519-8875)
Institutions
- Shandong Tumor Hospital (CN)
- Qilu Hospital of Shandong University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-29
- DOI
- https://doi.org/10.3389/fimmu.2025.1589379
- Citations
- 4
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 4.18