Development of a machine learning-based predictive nomogram for screening children with juvenile idiopathic arthritis: a pseudo-longitudinal study of 223,195 children in the United States

Using two well-validated predictor models, we developed nomograms for the early prediction of JIA in children based on the NSCH database. The tools are also available for parents and health professionals to utilize these nomograms. Our easy-to-use nomograms are not intended to replace the standard diagnostic methods. Still, they are designed to assist parents, clinicians, and researchers in better-estimating children's potential risk of JIA. We advise individuals utilizing our nomogram model to be mindful of potential pre-existing selection biases that may affect referrals and diagnoses.

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Publication Details

Journal
Frontiers in Public Health
Published
2025-05-29
DOI
https://doi.org/10.3389/fpubh.2025.1531764
Citations
1
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
Field-Weighted Citation Impact
1.77

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article

Development of a machine learning-based predictive nomogram for screening children with juvenile idiopathic arthritis: a pseudo-longitudinal study of 223,195 children in the United States

Heaven Hollender, Matthew E. Sprong, Yu-Sheng Lee, Junu Shrestha et al.
1 citations
Frontiers in Public Health
Autoimmune and Inflammatory Disorders Research
1.77
article

Development of a machine learning-based predictive nomogram for screening children with juvenile idiopathic arthritis: a pseudo-longitudinal study of 223,195 children in the United States

Heaven Hollender, Matthew E. Sprong, Yu-Sheng Lee, Junu Shrestha, Xueli Huang, Kira Gor
article en
1 citations

Abstract

Using two well-validated predictor models, we developed nomograms for the early prediction of JIA in children based on the NSCH database. The tools are also available for parents and health professionals to utilize these nomograms. Our easy-to-use nomograms are not intended to replace the standard diagnostic methods. Still, they are designed to assist parents, clinicians, and researchers in better-estimating children's potential risk of JIA. We advise individuals utilizing our nomogram model to be mindful of potential pre-existing selection biases that may affect referrals and diagnoses.

Frontiers in Public HealthVol. 13
Indiana University Health (US), Illinois Department of Public Health (US), Governors State University (US), Indiana University – Purdue University Indianapolis (US), University of Illinois at Springfield (US)
Health Resources and Services Administration, Maternal and Child Health Bureau
Peace, Justice and strong institutions
Openalex Percentile: Top 16%
Autoimmune and Inflammatory Disorders Research
1.77
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