Development of a machine learning-based predictive nomogram for screening children with juvenile idiopathic arthritis: a pseudo-longitudinal study of 223,195 children in the United States
Using two well-validated predictor models, we developed nomograms for the early prediction of JIA in children based on the NSCH database. The tools are also available for parents and health professionals to utilize these nomograms. Our easy-to-use nomograms are not intended to replace the standard diagnostic methods. Still, they are designed to assist parents, clinicians, and researchers in better-estimating children's potential risk of JIA. We advise individuals utilizing our nomogram model to be mindful of potential pre-existing selection biases that may affect referrals and diagnoses.
Authors
- Heaven Hollender
- Matthew E. Sprong (ORCID: https://orcid.org/0000-0002-6867-252X)
- Yu-Sheng Lee (ORCID: https://orcid.org/0000-0002-1018-2528)
- Junu Shrestha (ORCID: https://orcid.org/0000-0002-8683-2689)
- Xueli Huang
- Kira Gor
Institutions
- Indiana University Health (US)
- Illinois Department of Public Health (US)
- Governors State University (US)
- Indiana University – Purdue University Indianapolis (US)
- University of Illinois at Springfield (US)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2025-05-29
- DOI
- https://doi.org/10.3389/fpubh.2025.1531764
- Citations
- 1
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- Health Resources and Services Administration
- Maternal and Child Health Bureau