Integrated multi-omics analysis and experimental investigation of mitochondrial dynamics-related genes: molecular subtypes, immune landscape, and prognostic implications in lung adenocarcinoma
MD-related genes exhibit strong prognostic and immune subtyping value. The proposed risk model holds clinical potential, and MTCH2 may serve as a promising target for precision therapy in LUAD.
Authors
- Yao Yu (ORCID: https://orcid.org/0000-0002-2814-4482)
- Jincan Lin
- Yiling Jiang (ORCID: https://orcid.org/0000-0002-1236-7550)
- Junfan Pan (ORCID: https://orcid.org/0000-0002-6141-3883)
- Lijun Zeng (ORCID: https://orcid.org/0009-0009-1365-0567)
- Qihong Pan
- Jing Zhang (ORCID: https://orcid.org/0000-0002-8449-6554)
- Sixuan Wu (ORCID: https://orcid.org/0000-0001-7690-723X)
Institutions
- Fujian Medical University (CN)
- Shaoyang University (CN)
- First Affiliated Hospital of Xiamen University (CN)
- Fujian Provincial Cancer Hospital (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-29
- DOI
- https://doi.org/10.3389/fimmu.2025.1585505
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00