Adenosine deaminase and interleukin-1 receptor antagonist genetic polymorphisms among obese children with versus without metabolic dysfunction-associated fatty liver disease
The current study's findings support the possible genetic role of ADA G22A in childhood obesity, with a significant role for the IL-1RN SNP in the development of MAFLD in obese children. The triglyceride-to-HDL-C ratio was more useful than the VLDL/HDL-C ratio for predicting pediatric MAFLD.
Authors
- Mohammed H. Hassan (ORCID: https://orcid.org/0000-0003-2698-9438)
- AhmadMuhammad Taha
- Ali Helmi Bakri (ORCID: https://orcid.org/0000-0003-1156-8446)
- Hala M. Sakhr (ORCID: https://orcid.org/0000-0002-1925-054X)
Institutions
- South Valley University (EG)
Publication Details
- Journal
- Clinical and Experimental Pediatrics
- Published
- 2025-05-29
- DOI
- https://doi.org/10.3345/cep.2025.00731
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00