Generation of canine induced pluripotent stem cell-derived mesenchymal stem cells: Comparison of differentiation strategies and cell origins
Highly proliferative iMSCs expressing a high rate of MSC markers can be obtained from cUC-iPSCs via ectodermal induction. Our study demonstrated that the differentiation strategy and cell origin of ciPSCs play crucial roles in the generation of iMSCs.
Authors
- Kazuya EDAMURA (ORCID: https://orcid.org/0000-0002-2123-0716)
- Takumi Yoshida
- Chiaki Kawabata
- Shingo Hatoya (ORCID: https://orcid.org/0000-0001-5944-1394)
- Kikuya Sugiura (ORCID: https://orcid.org/0000-0003-3366-237X)
- Kazuto Kimura (ORCID: https://orcid.org/0009-0007-8029-9346)
- Kohei Shishida
- Masaya Tsukamoto (ORCID: https://orcid.org/0000-0002-3823-8992)
Institutions
- Nihon University (JP)
- Osaka Metropolitan University (JP)
- University of California, Davis (US)
Publication Details
- Journal
- Regenerative Therapy
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1016/j.reth.2025.05.008
- Citations
- 1
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- Japan Society for the Promotion of Science