Addressing Survivorship Bias in Neurocognitive Outcomes After Early Complex Cardiac Surgery Using Clustering and Propensity Scores
PS adjustment with clustering did not confirm survivorship bias. PS-adjusted models demonstrated stable Full Scale Intelligence Quotient and Visual Motor Integration scores over time, and inconsistent findings for General Adaptive Composite scores. Improved survival after more complex cardiac surgery was not associated with worse long-term neurocognitive outcomes.
Authors
- Irina A Dinu (ORCID: https://orcid.org/0000-0001-6925-623X)
- Gonzalo Garcia Guerra (ORCID: https://orcid.org/0000-0001-6407-0823)
- Ari R. Joffe (ORCID: https://orcid.org/0000-0002-4583-707X)
- Morteza Hajihosseini (ORCID: https://orcid.org/0000-0002-3303-5395)
- Gwen Y. Bond (ORCID: https://orcid.org/0000-0002-9700-0562)
- Joseph Atallah (ORCID: https://orcid.org/0000-0001-8763-2067)
- Charlene M.T. Robertson (ORCID: https://orcid.org/0000-0002-6306-4234)
- Sara Amiri (ORCID: https://orcid.org/0009-0005-8396-5311)
Institutions
- University of Alberta (CA)
- Glenrose Rehabilitation Hospital (CA)
Publication Details
- Journal
- CJC Pediatric and Congenital Heart Disease
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1016/j.cjcpc.2025.05.005
- Primary Topic
- Cardiac, Anesthesia and Surgical Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Children's Health Research Institute
- Women and Children's Health Research Institute